Effect of low-level BCR-ABL1 kinase domain mutations identified by next-generation sequencing in patients with chronic myeloid leukaemia: a population-based study

…, R Gale, E Bart-Smith, S Weston-Smith… - The Lancet …, 2019 - thelancet.com
Background Kinase domain mutations in BCR-ABL1 are associated with resistance to
tyrosine kinase inhibitors in patients with chronic myeloid leukaemia. Next-generation …

Translocation t (2; 7)(p12; q21-22) with dysregulation of the CDK6 gene mapping to 7q21-22 in a non-Hodgkin's lymphoma with leukemia

V Brito-Babapulle, AM Gruszka-Westwood, G Platt… - 2002 - repository.icr.ac.uk
Background and Objectives. A female patient presented with splenomegaly and
lymphocytosis with atypical lymphoid cell morphology, We identified t (2; 7)(p12; q21) …

Parvovirus infection and anaemia in a patient with AIDS: case report.

SA Mitchell, JM Welch, S Weston-Smith… - Sexually Transmitted …, 1990 - sti.bmj.com
Opportunistic infections such as Pneumocystis carinii pneumonia are well-recognised in
patients with the acquired immune deficiency syndrome (AIDS). Anaemia due to a variety of …

Thrombophilia.

S Weston-Smith, P Revell… - British journal of hospital …, 1989 - europepmc.org
Thrombophilia. - Abstract - Europe PMC Sign in | Create an account https://orcid.org Europe
PMC Menu About Tools Developers Help Contact us Helpdesk Feedback Twitter Blog Tech blog …

Severe folate-deficiency pancytopenia

V Clarke, S Weston-Smith - Case Reports, 2010 - casereports.bmj.com
Folate-deficiency anaemia occurs in about 4 per 100 000 people, although severe cases
causing moderate pancytopenia are rarer. We present the case of a significant folate …

Implementing access control to protect the confidentiality of patient information in clinical information systems in the acute hospital

I Denley, SW Smith - Health Informatics Journal, 1998 - journals.sagepub.com
In this paper, a practical approach to managing the confidentiality of patient information in
large-scale clinical information systems in the acute hospital is described. The traditional …

Primary systemic amyloidosis presenting as idiopathic inflammatory colitis

…, M Toqeer, I Hawley, S Weston-Smith… - Case …, 2011 - casereports.bmj.com
A 75-year old-female was referred with chest pain. She was fully investigated and it was felt
that her symptoms were non-cardiac. Four months later, she was seen in gastroenterology …

[HTML][HTML] Impact of finding of low level kinase domain mutations using ultra deep next generation sequencing in patients with chronic phase CML

…, EE Bart-Smith, R Gale, C Wykes, S Weston-Smith… - Blood, 2015 - Elsevier
Kinase domain (KD) mutations in the BCR-ABL1 gene are associated with resistance to
tyrosine kinase inhibitors (TKI) in chronic myeloid leukemia (CML). Next-generation …

The haemodynamic responses to venesection and the effects of cardiovascular disease

SHL Thomas, SW Smith, NGP Slater… - Clinical & Laboratory …, 1992 - Wiley Online Library
The haemodynamic effects of the venesection of one unit (450 ml) of blood over 9 min were
measured using non‐invasive techniques, in 14 healthy controls and 18 patients with …

[PDF][PDF] Wandering spleen: A mobile target for radiotherapy

K Gardner, S Weston Smith - American Journal of Hematology, 2013 - researchgate.net
CT monitoring of lung nodules throughout this period has afforded us ample radiology to
witness the normally located, albeit enlarged, spleen prior to radiotherapy (see Fig. 1a–c). In …