Herb-drug interactions: a literature review

Z Hu, X Yang, PCL Ho, SY Chan, PWS Heng, E Chan… - Drugs, 2005 - Springer
Herbs are often administered in combination with therapeutic drugs, raising the potential of
herb-drug interactions. An extensive review of the literature identified reported herb-drug …

Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs

S Zhou, SY Chan, BC Goh, E Chan, W Duan… - Clinical …, 2005 - Springer
Consistent with its highest abundance in humans, cytochrome P450 (CYP) 3A is responsible
for the metabolism of about 60% of currently known drugs. However, this unusual low …

MicroRNA-210: a unique and pleiotropic hypoxamir

SY Chan, J Loscalzo - Cell cycle, 2010 - Taylor & Francis
Inadequate oxygen availability or hypoxia induces a complex and still incompletely
understood set of adaptations that influence cellular survival and function. Many of these …

The genome sequence of the SARS-associated coronavirus

MA Marra, SJM Jones, CR Astell, RA Holt… - Science, 2003 - science.org
We sequenced the 29,751-base genome of the severe acute respiratory syndrome (SARS)–
associated coronavirus known as the Tor2 isolate. The genome sequence reveals that this …

[HTML][HTML] KBase: the United States department of energy systems biology knowledgebase

AP Arkin, RW Cottingham, CS Henry, NL Harris… - Nature …, 2018 - nature.com
Although similar integrative tools exist (Supplementary Note 2), no other open platform
shares all KBase's features, which include the following:(i) comprehensive support for data …

[HTML][HTML] Deleted in Colorectal Cancer (DCC) encodes a netrin receptor

K Keino-Masu, M Masu, L Hinck, ED Leonardo… - Cell, 1996 - cell.com
The guidance of developing axons in the nervous system is mediated partly by diffusible
chemoattractants secreted by axonal target cells. Netrins are chemoattractants for …

[HTML][HTML] The functional role of the ELR motif in CXC chemokine-mediated angiogenesis

RM Strieter, PJ Polverini, SL Kunkel… - Journal of Biological …, 1995 - ASBMB
In this study, we demonstrate that the CXC family of chemokines displays disparate
angiogenic activity depending upon the presence or absence of the ELR motif. CXC …

[PDF][PDF] MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2

SY Chan, YY Zhang, C Hemann, CE Mahoney… - Cell metabolism, 2009 - cell.com
Repression of mitochondrial respiration represents an evolutionarily ancient cellular
adaptation to hypoxia and profoundly influences cell survival and function; however, the …

[HTML][HTML] UNC-40, a C. elegans homolog of DCC (Deleted in Colorectal Cancer), is required in motile cells responding to UNC-6 netrin cues

SSY Chan, H Zheng, MW Su, R Wilk, MT Killeen… - Cell, 1996 - cell.com
Abstract UNC-6 netrin, a laminin-related protein secreted from neuroglia and neurons along
the ventral midline, orients migrating cells and pioneering growth cones on the nematode …

Alternative expression analysis by RNA sequencing

M Griffith, OL Griffith, J Mwenifumbo, R Goya… - Nature …, 2010 - nature.com
In alternative expression analysis by sequencing (ALEXA-seq), we developed a method to
analyze massively parallel RNA sequence data to catalog transcripts and assess differential …