User profiles for "author:Segundo R León"

Segundo R. León

Director General de Investigación y Responsabilidad Social, Universidad Privada San Juan …
Verified email at upsjb.edu.pe
Cited by 2232

[HTML][HTML] Early progression to active tuberculosis is a highly heritable trait driven by 3q23 in Peruvians

Y Luo, S Suliman, S Asgari, T Amariuta… - Nature …, 2019 - nature.com
Of the 1.8 billion people worldwide infected with Mycobacterium tuberculosis, 5–15% will
develop active tuberculosis (TB). Approximately half will progress to active TB within the first …

HIV self-testing in Peru: questionable availability, high acceptability but potential low linkage to care among men who have sex with men and transgender women

MJ Bustamante, KA Konda… - … journal of STD & …, 2017 - journals.sagepub.com
HIV status awareness is key to prevention, linkage-to-care and treatment. Our study
evaluated the accessibility and potential willingness of HIV self-testing among men who …

Peripheral Blood Mucosal-Associated Invariant T Cells in Tuberculosis Patients and Healthy Mycobacterium tuberculosis-Exposed Controls

S Suliman, A Gela, SC Mendelsohn… - The Journal of …, 2020 - academic.oup.com
Background In human blood, mucosal-associated invariant T (MAIT) cells are abundant T
cells that recognize antigens presented on non-polymorphic major histocompatibility …

[PDF][PDF] Chlamydia trachomatis infection and associated risk factors in a low-income marginalized urban population in coastal Peru

SR León, KA Konda, JD Klausner… - … de Salud Pública, 2009 - SciELO Public Health
OBJECTIVES: To estimate Chlamydia trachomatis (CT) infection prevalence and associated
risk factors among a low-income marginalized urban population in Peru. METHODS …

[HTML][HTML] HPV knowledge, burden and genital wart location among heterosexually identified versus homosexually identified men who have sex with men in Lima, Peru …

JT Galea, SR León, J Peinado, G Calvo, J Zamora… - BMJ open, 2017 - bmjopen.bmj.com
Objectives The relationship between sexual practices, identity and role among Latino men
who have sex with men (MSM) and HIV risk is the subject of ongoing investigation but less is …

A TCR β-chain motif biases toward recognition of human CD1 proteins

P Reinink, A Shahine, S Gras, TY Cheng… - The Journal of …, 2019 - journals.aai.org
High-throughput TCR sequencing allows interrogation of the human TCR repertoire,
potentially connecting TCR sequences to antigenic targets. Unlike the highly polymorphic …

Individual-level characteristics associated with oral HIV test acceptability among Peruvian men who have sex with men and transgender women: a cross-sectional …

JA Flores, B Brown, SR León, H Sánchez… - Sexually transmitted …, 2018 - sti.bmj.com
Objectives Peruvian men who have sex with men (MSM) and transgender women (TGW) are
highly vulnerable to HIV infection (HIV), but stigma, access issues and fear of venipuncture …

Progression of recent Mycobacterium tuberculosis exposure to active tuberculosis is a highly heritable complex trait driven by 3q23 in Peruvians

Y Luo, S Suliman, S Asgari, T Amariuta, R Calderon… - bioRxiv, 2018 - biorxiv.org
Among 1.8 billion people worldwide infected with Mycobacterium tuberculosis, 5-15% are
expected to develop active tuberculosis (TB). Approximately half of these will progress to …

Pretreatment hiv drug resistance and virologic outcomes to first-line antiretroviral therapy in Peru

J Soria, R Mugruza, M Levine, SR León… - AIDS Research and …, 2019 - liebertpub.com
Access to nucleoside reverse transcriptase inhibitor (NRTI) and non-nucleoside reverse
transcriptase inhibitor (NNRTI) first-line antiretroviral therapy (ART) for HIV has been …

Dual TCR-α expression on mucosal-associated invariant T cells as a potential confounder of TCR interpretation

S Suliman, L Kjer-Nielsen, SK Iwany… - The Journal of …, 2022 - journals.aai.org
Mucosal-associated invariant T (MAIT) cells are innate-like T cells that are highly abundant
in human blood and tissues. Most MAIT cells have an invariant TCRα-chain that uses T cell …