Objectives The data on STIs control and HIV prevention is limited among MSM population. To examine STIs control strategies for HIV prevention in a community-based cohort of HIV-negative MSM, community intervention trail was conducted between 2009 and 2011. This report mainly discussed baseline survey results.

Methods This study was conducted in MSM community of four mid-sized cities from Jul. to Sep. 2009. All participants were recruited through venue-based recruitment, complemented by peer referral using snowball method, Questionnaire were completed in STD clinics or VCT centers. Blood samples were collected for HIV, syphilis and HSV-2 tests, and urine sample for CT/NG PCR tests.

Results 35.3% participants self-identified as homosexual and 44.7% bisexual. The most popular way to seek male sexual partners was internet (38.4%). 15.9% of participants had provided or acquired sex services with male, while 19.1% of respondents reported unprotected anal intercourse (UAI) in the last sex services. 3.8% of participants had experienced sadism & masochism(SM). In past 6 months, 80.8% of participants had anal sex with man and 29.0% reported UAI during the last intercourse. 38.5% of participants reported having had sex with woman and only 45.2% of those reported using condom during the last intercourse with woman. 18.0% of participants involved in commercial sex services had taken drugs such as methamphetamine, Ketamine and MDMA.10.6% of participants was HIV infection. 34.4% of participants is TP-ELISA positive results indicated a history of syphilis infection, and 20.9% were both positive results of ELISA and TRUST indicated active syphilis. 3.0% of participants were tested as NG infection, 6.8% was CT infected, and 16.2% were HSV-2 infected. Significant factors associated with HIV infection were self-reported STD infection history [AOR=2.1, 95% CI: 1.29% to 4.26%], syphilis infection [AOR=2.70, 95% CI: 1.81% to 4.04%], and HSV-2 infection [AOR=3.07, 95% CI: 2.09% to 4.50%].

Conclusions MSM have been potential bridge-population for HIV/STIs from most-at-risk population to general population. Intervention activities should target the internet, sexual social networks, and certain subpopulations such as those taking drugs in commercial sex services or infected with STIs. Friendly and high-quality STIs service should reach to MSM who do not attend STD clinics. Campaigns are urgent not only to boost individual condom use but also to create culture for condom use in MSM community.